肾衰竭中的抗菌药物。
Antibacterial agents in renal failure.
作者信息
Livornese L L, Benz R L, Ingerman M J, Santoro J
机构信息
Lankenau Hospital, Wynnewood, Pennsylvania, USA.
出版信息
Infect Dis Clin North Am. 1995 Sep;9(3):591-614.
PMID:7490435
Abstract
This article provides background information on the pharmacokinetics of antimicrobial agents in patients with normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure. Specific mention is made of aminoglycoside dosing, dosage adjustment in dialysis, and antibiotic toxicity in renal failure.
摘要
本文提供了关于抗菌药物在肾功能正常和受损患者体内药代动力学的背景信息。文中给出了表格，以便快速确定不同程度肾衰竭患者的合适剂量。特别提到了氨基糖苷类药物的给药、透析时的剂量调整以及肾衰竭时的抗生素毒性。
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