Charlton A, While D
Cancer Research Campaign Education and Child Studies Research Group, School of Epidemiology and Health Sciences, University of Manchester.
Arch Dis Child. 1995 Oct;73(4):294-7. doi: 10.1136/adc.73.4.294.
The reasons why adult smokers have lower blood pressure than non-smokers have not been determined. It is possible that low blood pressure might precede the onset of smoking. This study investigates this hypothesis in a national cohort study in Britain. Blood pressures and pulse rates taken on a sample of 5019 members of the British Birth Cohort Study (BCS 70) at the age of 10 years were analysed in relation to self reported smoking behaviour at age 16+ years. Prospectively, those children who had lower diastolic blood pressure or pulse rate at age 10 were more likely to have smoked by age 16+ years. Using analysis of variance, pulse rate was significantly related to smoking in young men (p < 0.001). Seventy per cent of those with lower pulse (below the 10th centile), 58% with medium pulse, and 52% with the higher pulse (above the 90th centile) had ever smoked by age 16+ years. In young women, pulse rate (p = 0.003), diastolic pressure (p = 0.024), and systolic pressure (p = 0.032) at age 10 were all significantly related to smoking at age 16. This longitudinal study found that lower blood pressure and slower pulse rate were related to the onset of smoking in children. More research is needed on this new observation.
成年吸烟者血压低于非吸烟者的原因尚未确定。低血压可能在吸烟开始之前就已出现。本研究在英国的一项全国队列研究中对这一假设进行了调查。对英国出生队列研究(BCS 70)中5019名成员在10岁时测量的血压和脉搏率,与他们16岁及以上时自我报告的吸烟行为进行了分析。前瞻性地看,那些在10岁时舒张压或脉搏率较低的儿童在16岁及以上时更有可能吸烟。通过方差分析,脉搏率与年轻男性的吸烟情况显著相关(p < 0.001)。脉搏率较低(低于第10百分位数)的人中,70%在16岁及以上时曾经吸烟;脉搏率中等的人中,58%曾经吸烟;脉搏率较高(高于第90百分位数)的人中,52%曾经吸烟。在年轻女性中,10岁时的脉搏率(p = 0.003)、舒张压(p = 0.024)和收缩压(p = 0.032)均与16岁时的吸烟情况显著相关。这项纵向研究发现,较低的血压和较慢的脉搏率与儿童吸烟的开始有关。需要对这一新观察结果进行更多研究。