Modena V, Migone N, Daneo V, Carbonara A O, di Vittorio S, Viara M
Ann Rheum Dis. 1978 Dec;37(6):510-2. doi: 10.1136/ard.37.6.510.
Nine cases from among 64 patients with ankylosing spondylitis (AS) are described. In addition to bilateral sacroiliitis these cases had a peculiar type of spondylodiscitis characterised by quite diffuse and marked sclerosis of multiple vertebral bodies, with only minimal erosions of the adjacent vertebral plates while classical syndesmophytosis was absent. The antigen HLA-B27 was found only in 1 of these 9 cases. This type of spondylodiscitis could discriminate among all the patients with AS a subgroup with a peculiar clinical pattern and a probably distinctive pathological mechanism.
本文描述了64例强直性脊柱炎（AS）患者中的9例。除双侧骶髂关节炎外，这些病例有一种特殊类型的脊椎椎间盘炎，其特征为多个椎体出现相当弥漫且明显的硬化，相邻椎板仅有轻微侵蚀，而无典型的韧带骨赘形成。在这9例患者中仅1例发现抗原HLA - B27。这种类型的脊椎椎间盘炎可以在所有AS患者中区分出一个具有特殊临床模式和可能独特病理机制的亚组。
