各种贫血类型中红细胞δ-氨基-γ-酮戊酸脱水酶活性及δ-氨基-γ-酮戊酸浓度的变化
Erythrocyte delta-aminolaevulinic acid dehydratase activity and changes in delta-aminolaevulinic acid concentration in various forms of anaemia.
作者信息
Campbell B C, Meredith P A, Moore M R, Goldberg A
出版信息
Br J Haematol. 1978 Nov;40(3):397-400. doi: 10.1111/j.1365-2141.1978.tb05811.x.
Abstract
Whole blood delta-aminolaevulinic acid (ALA) concentrations and erythrocyte ALA dehydratase activity have been measured in patients with iron deficiency anaemia, megaloblastic anaemia and secondary anaemia, and in normal subjects. ALA concentration was found to be significantly increased in all types of anaemia compared with normal. Erythrocyte ALA dehydratase activity was significantly increased in iron deficiency and megaloblastic anaemia but not in secondary anaemia.
摘要
已对缺铁性贫血、巨幼细胞贫血和继发性贫血患者以及正常受试者的全血δ-氨基乙酰丙酸（ALA）浓度和红细胞ALA脱水酶活性进行了测定。结果发现，与正常情况相比，所有类型贫血患者的ALA浓度均显著升高。缺铁性贫血和巨幼细胞贫血患者的红细胞ALA脱水酶活性显著升高，但继发性贫血患者则不然。
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