肾性高血压犬的肾脏前列腺素
Renal prostaglandins in renal hypertensive dogs.
作者信息
Dighe K K, Smith G W, Ungar A, Whelpdale P H
出版信息
Clin Sci Mol Med. 1978 May;54(5):561-6. doi: 10.1042/cs0540561.
PMID:750158
Abstract
- Hypertension produced in two-kidney Goldblatt dogs was accompanied by a transient fluid retention, reaching a maximum 4 days after clamping. 2. Prostaglandin E and F concentrations in venous blood from the intact kidney also rose transiently, showing a maximum by the fifth day. 3. The rise in prostaglandin release from the intact kidney may be related to the fluid retention.
摘要
- 双肾型Goldblatt犬产生的高血压伴有短暂的液体潴留，在夹闭后4天达到最大值。2. 来自完整肾脏的静脉血中前列腺素E和F的浓度也短暂升高，在第5天达到最大值。3. 完整肾脏中前列腺素释放的增加可能与液体潴留有关。
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