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肿瘤标志物的转化研究进展。

Translational progress on tumor biomarkers.

机构信息

Key Laboratory of Longevity and Aging-Related Diseases, Ministry of Education Nanning, China ; Center for Translational Medicine, Guangxi Medical University Nanning, China.

Department of Urology and Pathology, School of Medicine, University of Michigan Ann Arbor, Michigan, USA.

出版信息

Thorac Cancer. 2015 Nov;6(6):665-71. doi: 10.1111/1759-7714.12294. Epub 2015 Jul 27.

Abstract

There is an urgent need to apply basic research achievements to the clinic. In particular, mechanistic studies should be developed by bench researchers, depending upon clinical demands, in order to improve the survival and quality of life of cancer patients. To date, translational medicine has been addressed in cancer biology, particularly in the identification and characterization of novel tumor biomarkers. This review focuses on the recent achievements and clinical application prospects in tumor biomarkers based on translational medicine.

摘要

迫切需要将基础研究成果应用于临床。具体而言,应当根据临床需求由 bench 研究人员开展机制研究,以提高癌症患者的生存率和生活质量。迄今为止,转化医学已在癌症生物学中得到了研究,特别是在新型肿瘤标志物的鉴定和特征描述方面。本文重点介绍了基于转化医学的肿瘤标志物的最新研究进展和临床应用前景。

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