Hunter D J, McKee C M, Sanderson C F, Black N A
Department of Public Health and Policy, London School of Hygiene and Tropical Medicine.
J Epidemiol Community Health. 1994 Feb;48(1):58-64. doi: 10.1136/jech.48.1.58.
The use of formal consensus development to determine appropriate indications for prostatectomy and to identify factors underlying clinical decisions about appropriateness is described.
A nominal group technique was used.
The study took place in an academic research institution.
The panel consisted of six urologists and three general practitioners.
The panel identified agreed indications for prostatectomy, expressed in terms of different combinations of type of retention, type and severity of symptoms, and level of comorbidity. Agreement was reached for 67% of the indications considered. For acute on chronic retention, surgery is indicated, regardless of symptom severity, if life expectancy is greater than one year. For acute or chronic retention, surgery is generally indicated if symptoms are severe, or if symptoms are moderate and life expectancy is greater than five years. For patients with neither acute nor chronic retention, surgery is indicated if symptoms are severe, or if these are moderate and life expectancy is greater than five years. For chronic or acute retention surgery is inappropriate if symptoms are mild and life expectancy is less than one year, or if there is no retention and only mild symptoms. An "appropriateness score" was developed. This confirmed that in general the ratings were internally consistent, that the panel attached little weight to mild symptoms, that a combination of irritative and obstructive symptoms was no more indicative of surgery than obstructive symptoms alone, and that the type of symptom was less important than the other factors considered.
The results provide a basis for population based surveys of the need for prostatectomy.
描述运用正式的共识发展方法来确定前列腺切除术的合适适应症,并识别有关适用性的临床决策背后的因素。
采用了名义群体技术。
该研究在一所学术研究机构进行。
小组由六名泌尿科医生和三名全科医生组成。
小组确定了前列腺切除术的一致适应症,以潴留类型、症状类型和严重程度以及合并症水平的不同组合来表示。对于所考虑的适应症,67%达成了共识。对于慢性潴留急性发作,如果预期寿命大于一年,则无论症状严重程度如何,均建议手术。对于急性或慢性潴留,如果症状严重,或者症状为中度且预期寿命大于五年,一般建议手术。对于既无急性也无慢性潴留的患者,如果症状严重,或者症状为中度且预期寿命大于五年,则建议手术。对于慢性或急性潴留,如果症状轻微且预期寿命小于一年,或者没有潴留且只有轻微症状,则不适合手术。制定了一个“适用性评分”。这证实了总体而言评分在内部是一致的,小组对轻微症状的权重较低,刺激性和梗阻性症状的组合并不比单独的梗阻性症状更能表明需要手术,并且症状类型不如所考虑的其他因素重要。
研究结果为基于人群的前列腺切除术需求调查提供了依据。