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霍乱弧菌脂多糖的免疫化学特性

Immunochemical properties of Vibrio cholerae LPS.

作者信息

Bukovský M, Ciznár I

机构信息

Faculty of Pharmacy, Comenius University, Bratislava.

出版信息

Folia Microbiol (Praha). 1993;38(6):519-23. doi: 10.1007/BF02814407.

DOI:10.1007/BF02814407
PMID:7512065
Abstract

Immunochemical analysis of LPS isolated from Vibrio cholerae O1 and non O1 showed that this macromolecular complex shares common antigenic epitopes in the sugar moiety. The epitopes can be detected after mild alkaline hydrolysis of LPS in vitro. Membrane-associating activity of both O1 and non O1 LPS did not indicate any differences of the species.

摘要

对从霍乱弧菌O1和非O1分离出的脂多糖进行免疫化学分析表明，这种大分子复合物在糖部分具有共同的抗原表位。这些表位在体外对脂多糖进行温和碱性水解后可以被检测到。O1和非O1脂多糖的膜结合活性并未显示出种属间的任何差异。

相似文献

1
Immunochemical properties of Vibrio cholerae LPS.霍乱弧菌脂多糖的免疫化学特性
Folia Microbiol (Praha). 1993;38(6):519-23. doi: 10.1007/BF02814407.
2
Immunochemical aspects of lipopolysaccharide of Vibrio cholerae O139 Bengal, a new epidemic strain for recent, fast-spreading cholera in the Indian subcontinent.霍乱弧菌O139孟加拉型脂多糖的免疫化学方面，这是一种近期在印度次大陆快速传播的霍乱新流行菌株。
Prog Clin Biol Res. 1995;392:161-6.
3
Immunochemical characterization of an Ogawa-Inaba common antigenic determinant of Vibrio cholerae O1.霍乱弧菌O1小川型-稻叶型共同抗原决定簇的免疫化学特性
Microbiology (Reading). 1999 Sep;145 ( Pt 9):2477-2484. doi: 10.1099/00221287-145-9-2477.
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O-antigenic lipopolysaccharides isolated from a marine Vibrio, bio-serogroup 1875, possessing an antigenic factor in common with O1 Vibrio cholerae.从海洋弧菌生物血清群1875中分离出的O抗原性脂多糖，与O1霍乱弧菌具有共同的抗原因子。
J Gen Microbiol. 1988 Jul;134(7):1827-33. doi: 10.1099/00221287-134-7-1827.
5
An N-[(R)-(-)-2-hydroxypropionyl]-alpha-L-perosamine homopolymer constitutes the O polysaccharide chain of the lipopolysaccharide from Vibrio cholerae O144 which has antigenic factor(s) in common with V. cholerae O76.一种N-[(R)-(-)-2-羟基丙酰基]-α-L-过氧胺均聚物构成了霍乱弧菌O144脂多糖的O多糖链，该霍乱弧菌O144与霍乱弧菌O76具有共同的抗原因子。
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Carbohydr Res. 1998 Jan;306(1-2):163-70. doi: 10.1016/s0008-6215(97)10052-0.
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The O polysaccharide chain of the lipopolysaccharide from Vibrio cholerae O76 is a homopolymer of N-[(S)-(+)-2-hydroxypropionyl]-alpha-L-perosamine.霍乱弧菌O76脂多糖的O多糖链是N-[(S)-(+)-2-羟基丙酰基]-α-L-过氧胺的同聚物。
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Relationship between structure and antigenicity of O1 Vibrio cholerae lipopolysaccharides.
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10
N-3-hydroxypropionyl-alpha-D-perosamine homopolymer constituting the O-chain of lipopolysaccharides from Vibrio bioserogroup 1875 possessing antigenic factor(s) in common with O1 Vibrio cholerae.构成来自弧菌生物血清群1875的脂多糖O链的N-3-羟基丙酰基-α-D-紫苏糖均聚物，其具有与霍乱弧菌O1共同的抗原因子。
Biochem J. 1993 Jun 1;292 ( Pt 2)(Pt 2):531-5. doi: 10.1042/bj2920531.

引用本文的文献

1
Immunochemical analysis of lipopolysaccharide-like component extracted from Borrelia burgdorferi sensu lato.对莱姆病螺旋体复合群中提取的脂多糖样成分进行免疫化学分析。
Folia Microbiol (Praha). 2004;49(5):625-9. doi: 10.1007/BF02931545.

本文引用的文献

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Effect of Alkali on the Immunological Reactivity of Lipopolysaccharide from Salmonella typhimurium.碱对鼠伤寒沙门氏菌脂多糖免疫反应性的影响。
Infect Immun. 1970 Nov;2(5):549-55. doi: 10.1128/iai.2.5.549-555.1970.
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Immunochemical studies of the O-antigens of Vibrio cholerae. The constitution of a lipopolysaccharide from V. cholerae 569B (Inaba).
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Production of cholera-like enterotoxin by a Vibrio cholerae non-O1 strain isolated from the environment.从环境中分离出的一株非O1群霍乱弧菌产生霍乱样肠毒素。
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Sugar composition of lipopolysaccharides of family Vibrionaceae. Absence of 2-keto-3-deoxyoctonate (KDO) except in Vibrio parahaemolyticus O6.
Microbiol Immunol. 1982;26(8):649-64. doi: 10.1111/j.1348-0421.1982.tb00209.x.
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Diseases of humans (other than cholera) caused by vibrios.由弧菌引起的人类疾病（霍乱除外）。
Annu Rev Microbiol. 1980;34:341-67. doi: 10.1146/annurev.mi.34.100180.002013.
6
Vibrio factors cause rapid fluid accumulation in suckling mice.弧菌因子可导致乳鼠体内迅速积液。
Infect Immun. 1983 Jun;40(3):1083-91. doi: 10.1128/iai.40.3.1083-1091.1983.
7
Evidence that a non-O1 Vibrio cholerae produces enterotoxin that is similar but not identical to cholera enterotoxin.有证据表明，非O1群霍乱弧菌产生的肠毒素与霍乱肠毒素相似但并不相同。
Infect Immun. 1983 Sep;41(3):896-901. doi: 10.1128/iai.41.3.896-901.1983.
8
Environmental and human isolates of Vibrio cholerae and Vibrio parahaemolyticus produce a Shigella dysenteriae 1 (Shiga)-like cytotoxin.霍乱弧菌和副溶血性弧菌的环境及人体分离株可产生一种痢疾志贺菌1型（志贺）样细胞毒素。
Lancet. 1984 Jan 14;1(8368):77-8. doi: 10.1016/s0140-6736(84)90006-0.
9
Isolation of nonagglutinable vibrios from an enteritis outbreak in Czechoslovakia.从捷克斯洛伐克一次肠炎暴发中分离出不可凝集弧菌。
J Infect Dis. 1968 Feb;118(1):25-31. doi: 10.1093/infdis/118.1.25.
10
Relation of structure to function in bacterial O-antigens. V. Nature of active sites in endotoxic lipopolysaccharides of Serratia marcescens.细菌O抗原中结构与功能的关系。V. 粘质沙雷氏菌内毒素脂多糖中活性位点的性质。
Ann N Y Acad Sci. 1966 Jun 30;133(2):604-21. doi: 10.1111/j.1749-6632.1966.tb52392.x.