Maurelli M, Marchioni E, Tartara A
Istituto Neurologico C. Mondino, Università di Pavia.
Boll Soc Ital Biol Sper. 1993 Sep;69(9):571-7.
The involvement of catecholaminergic and gabaergic transmission in the electrocortical pattern induced by centrally administered galanin was investigated in the rabbit. The inhibition of catecholamine synthesis by both DDC and alphaMPT potentiated the EEG effect of the peptide. Baclofen and muscimol significantly enhanced the EEG response to GAL. However the interaction between the peptide and gabaergic transmission seemed mainly to involve the type A receptor system.
在家兔中研究了中枢给予甘丙肽所诱导的电皮层模式中儿茶酚胺能和γ-氨基丁酸能传递的参与情况。DDC和α-甲基酪氨酸对儿茶酚胺合成的抑制增强了该肽的脑电图效应。巴氯芬和蝇蕈醇显著增强了对甘丙肽的脑电图反应。然而，该肽与γ-氨基丁酸能传递之间的相互作用似乎主要涉及A型受体系统。
