Wiczkowski A, Dyla L, Sawaryn T, Grzeszczak W
I Klinika Chorób Zakaźnych Slaskiej Akademii Medycznej w Bytomiu.
Przegl Epidemiol. 1993;47(4):421-5.
The aim of the study, was to evaluate the excretion of amylase, lysozyme and beta 2 microglobulin (B2-M) in patients with acute and chronic virus B hepatitis. The gathered findings show the maintained ability of tubules cells to reabsorption lysozyme and B2-M. The elevated excretion of amylase in the urine of patients with acute viral hepatitis show the transient decrease of abilities to absorb this enzyme by teh cells of the tubules. It may be caused by the saturation of the catabolic mechanism of the proteins in tubule cells as well as the decrease of their energetic abilities due to toxic activity of bilirubin and bile acids.
本研究的目的是评估急慢性乙型病毒性肝炎患者淀粉酶、溶菌酶和β2微球蛋白（B2-M）的排泄情况。收集的研究结果表明肾小管细胞保持了重吸收溶菌酶和B2-M的能力。急性病毒性肝炎患者尿中淀粉酶排泄增加，表明肾小管细胞吸收该酶的能力暂时下降。这可能是由于肾小管细胞蛋白质分解代谢机制饱和以及胆红素和胆汁酸的毒性作用导致其能量代谢能力下降所致。
