Ramanan S V, Mesimeris V, Brink P R
Department of Physiology and Biophysics, State University of New York at Stony Brook 11794-8661.
Biophys J. 1994 Apr;66(4):989-95. doi: 10.1016/S0006-3495(94)80880-X.
We present an exact solution to the linearized Nernst-Planck-Poisson equation for spherically symmetric current flow. This solution differs from Levitt's solution (Levitt, D. G. 1992. Biophys. J., Eq. A5) by its dependence on an additional parameter, which is equal to the net ion flux for monovalent ion-selective channels. For ion-selective channels, this solution may provide better boundary conditions to modelling the flow in the channel pore itself, although only at low salt concentrations. We use the solution to estimate the effects of flux interaction between closely packed channels.
我们给出了球对称电流线性化能斯特 - 普朗克 - 泊松方程的精确解。该解与莱维特的解(莱维特,D. G. 1992.《生物物理杂志》,式A5)的不同之处在于它依赖于一个额外参数,该参数等于单价离子选择性通道的净离子通量。对于离子选择性通道,此解可能为模拟通道孔本身的流动提供更好的边界条件,尽管仅在低盐浓度下。我们用该解来估计紧密排列通道之间通量相互作用的影响。