在正常日本个体的磁共振图像上发现的偶发性白质病变——与年龄和高血压的相关性

Incidental white matter lesions identified on magnetic resonance images of normal Japanese individuals--correlation with age and hypertension.

作者信息

Oyama H, Kida Y, Tanaka T, Iwakoshi T, Niwa M, Kobayashi T

机构信息

Department of Neurosurgery, Komaki City Hospital, Aichi.

出版信息

Neurol Med Chir (Tokyo). 1994 May;34(5):286-90. doi: 10.2176/nmc.34.286.

DOI:10.2176/nmc.34.286

PMID:7519749

Abstract

Incidental white matter high-intensity lesions are frequently seen on T2-weighted magnetic resonance (MR) images of the brain in older people. The incidence increases with advancing age or hypertension. Brain MR images of 59 normal individuals were examined to analyze this phenomenon. The total number of white matter high-intensity lesions correlated significantly with age (p = 0.004) or systolic blood pressure (p = 0.03). The 60- to 69-year-old group demonstrated a very close correlation of white matter lesions with systolic (p = 0.02) and diastolic blood pressure (p = 0.01), in contrast to the 50- to 59-year-old group. Hypertensive subjects in their 60s are thought to develop more white matter lesions than subjects in their 50s.

摘要

在老年人脑部的T2加权磁共振（MR）图像上经常可以看到偶然发现的白质高信号病变。其发病率随年龄增长或高血压而增加。对59名正常个体的脑部MR图像进行了检查以分析这一现象。白质高信号病变的总数与年龄（p = 0.004）或收缩压（p = 0.03）显著相关。与50至59岁年龄组相比，60至69岁年龄组的白质病变与收缩压（p = 0.02）和舒张压（p = 0.01）呈现出非常密切的相关性。据认为，60多岁的高血压患者比50多岁的患者会出现更多的白质病变。