Varki A
Glycobiology Program, Cancer Center, University of California, San Diego, La Jolla 92093.
Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7390-7. doi: 10.1073/pnas.91.16.7390.
The selectins initiate many critical interactions among blood cells. The volume of information and diversity of opinions on the nature of the biologically relevant ligands for selectins is remarkable. This review analyzes the matter and suggests the hypothesis that at least some of the specificity may involve recognition of "clustered saccharide patches."
选择素引发血细胞间许多关键的相互作用。关于选择素生物学相关配体的性质，信息之丰富和观点之多样令人瞩目。本综述分析了这一问题，并提出假说，即至少部分特异性可能涉及对“聚集糖基斑块”的识别。
