CD20：B淋巴细胞细胞周期进程的调节因子。
CD20: a regulator of cell-cycle progression of B lymphocytes.
作者信息
Tedder T F, Engel P
机构信息
Dept of Immunology, Duke University Medical Center, Durham, NC 27710.
出版信息
Immunol Today. 1994 Sep;15(9):450-4. doi: 10.1016/0167-5699(94)90276-3.
PMID:7524522
Abstract
CD20 is a B-cell-specific cell-surface molecule with four membrane-spanning domains, as well as cytoplasmic N- and C-terminal domains. Here, Thomas Tedder and Pablo Engel discuss the suggestion that CD20 is a regulator of transmembrane Ca2+ conductance and plays an important functional role in B-cell activation, proliferation and differentiation.
摘要
CD20是一种B细胞特异性细胞表面分子，具有四个跨膜结构域以及胞质N端和C端结构域。在此，托马斯·特德和巴勃罗·恩格尔讨论了关于CD20是跨膜Ca2+电导调节剂并在B细胞活化、增殖和分化中发挥重要功能作用的观点。
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