Boxall E, Skidmore S, Evans C, Nightingale S
Regional Virus Laboratory, Public Health Laboratory, Birmingham Heartlands Hospital.
Epidemiol Infect. 1994 Dec;113(3):523-8. doi: 10.1017/s0950268800068539.
A total of 3522 samples of serum, collected anonymously from women attending an antenatal clinic, was tested for hepatitis B surface antigen and antibody to hepatitis C. The prevalence of anti-HCV was low; only five confirmed positives were found (0.14%). The prevalence of hepatitis B overall was 0.56%, but was 1.04% in women from immigrant groups. Hepatitis B carriage is therefore four times more common than hepatitis C carriage in the antenatal population comprised of various ethnic origins. The patterns of infection in the two viruses are reversed, hepatitis B being more common in Asian, S.E. Asian and West Indian mothers and hepatitis C being more common in mothers of white Caucasian origin. Routine antenatal screening for anti-HCV is discussed.
共采集了3522份匿名的血清样本，这些样本来自于在产前诊所就诊的女性，对其进行了乙肝表面抗原和丙肝抗体检测。抗丙肝病毒（anti-HCV）的流行率较低；仅发现5例确诊阳性（0.14%）。乙肝总体流行率为0.56%，但在移民群体女性中为1.04%。因此，在由不同种族组成的产前人群中，乙肝携带者比丙肝携带者常见四倍。两种病毒的感染模式相反，乙肝在亚洲、东南亚和西印度裔母亲中更常见，而丙肝在白种人母亲中更常见。文中讨论了抗丙肝病毒的常规产前筛查。
