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采用5-氟尿嘧啶-链脲霉素与5-氟尿嘧啶-达卡巴嗪交替联合方案治疗晚期甲状腺髓样癌。降钙素瘤研究小组(GETC)。

Treatment of advanced medullary thyroid cancer with an alternating combination of 5 FU-streptozocin and 5 FU-dacarbazine. The Groupe d'Etude des Tumeurs a Calcitonine (GETC).

作者信息

Schlumberger M, Abdelmoumene N, Delisle M J, Couette J E

机构信息

Institut Gustave-Roussy, Villejuif, France.

出版信息

Br J Cancer. 1995 Feb;71(2):363-5. doi: 10.1038/bjc.1995.73.

Abstract

Combinations of 5-fluorouracil (5-FU) and streptozocin and 5-FU and dacarbazine were given alternately to 20 patients with metastatic medullary thyroid carcinoma. Three partial responses and 11 long-term stabilizations were observed. No unexpected toxicity occurred.

摘要

对20例转移性甲状腺髓样癌患者交替给予5-氟尿嘧啶(5-FU)与链脲佐菌素及5-FU与达卡巴嗪联合治疗。观察到3例部分缓解和11例长期病情稳定。未出现意外毒性反应。

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