Cosgrove D M, Loop F D, Irarrazaval M J, Groves L K, Taylor P C, Golding L A
Ann Thorac Surg. 1978 Oct;26(4):357-63. doi: 10.1016/s0003-4975(10)62904-9.
To determine the effect of aneurysmectomy solely or combined with direct revascularization, 349 consecutive surgical patients treated between 1962 and 1972 were retrospectively reviewed. The minimum follow-up for survivors was 5 years (mean, 7 years). Single-vessel disease occurred in 171 (49%) and only ventricular aneurysmectomy was performed (Group 1). Multiple-vessel disease was found in 178 (51%), of whom 79 (44%) had resection of a ventricular aneurysm and revascularization of all major obstructed vessels (Group 2); 99 (56%) had aneurysm resection and incomplete revascularization (Group 3). Survival at 7 years was 69% for Group 1, 65% for Group 2, and 51% for Group 3. Actuarial survival at 7 years was 70% for patients operated on for angina; 55% for congestive heart failure; 57% for a combination of angina and heart failure; and 64% for ventricular tachycardia. Survival of patients with multiple-vessel disease who underwent aneurysmectomy and complete revascularization was similar to that of patients with single-vessel disease who underwent aneurysmectomy alone. Longevity is adversely influenced by incomplete revascularization (p less than 0.005) and preoperative congestive heart failure (p less than 0.005).
为了确定单纯动脉瘤切除术或联合直接血运重建术的效果,我们对1962年至1972年间连续接受手术治疗的349例患者进行了回顾性研究。对幸存者的最短随访时间为5年(平均7年)。单支血管病变患者171例(49%),仅接受了心室动脉瘤切除术(第1组)。多支血管病变患者178例(51%),其中79例(44%)接受了心室动脉瘤切除术并对所有主要阻塞血管进行了血运重建(第2组);99例(56%)接受了动脉瘤切除术但血运重建不完全(第3组)。第1组7年生存率为69%,第2组为65%,第3组为51%。因心绞痛接受手术患者的7年精算生存率为70%;因充血性心力衰竭患者为55%;因心绞痛和心力衰竭合并症患者为57%;因室性心动过速患者为64%。接受动脉瘤切除术并完全血运重建的多支血管病变患者的生存率与仅接受动脉瘤切除术的单支血管病变患者相似。血运重建不完全(p<0.005)和术前充血性心力衰竭(p<0.005)对生存期有不利影响。