摄入胭脂红后发生食物过敏反应。
Food anaphylaxis following ingestion of carmine.
作者信息
Beaudouin E, Kanny G, Lambert H, Fremont S, Moneret-Vautrin D A
机构信息
Service d'Immunologie Clinique et d'Allergologie, CHRU de Nancy, Hôpitaux de Brabois, Rue du Morvan, Vandoeuvre-les-Nancy, France.
出版信息
Ann Allergy Asthma Immunol. 1995 May;74(5):427-30.
BACKGROUND
The risk of sensitization to reactive dyes is well established. The clinical situation is caused most often by synthetic azo dyes and triphenylmethane derivatives but natural dyes such as carmine extracted from dried female insects, Coccus cacti (cochineal), have been incriminated.
OBJECTIVE
Study of a case of anaphylaxis after ingestion of yogurt to establish the responsibility of carmine.
METHOD
Case report of a patient who received skin prick test and leukocyte histamine release test with carmine and yogurt.
CONCLUSIONS
This case provided evidence of an IgE-dependent mechanism and draws attention to the triggering dose of carmine (1 mg) although the acceptable daily intake is up to 5.0 mg per kg of body weight.
背景
对活性染料致敏的风险已得到充分证实。临床情况最常由合成偶氮染料和三苯甲烷衍生物引起，但天然染料如从干燥雌虫胭脂虫（胭脂虫红）中提取的胭脂红也被认为有责任。
目的
研究一例摄入酸奶后发生过敏反应的病例，以确定胭脂红的责任。
方法
对一名接受了胭脂红和酸奶皮肤点刺试验及白细胞组胺释放试验的患者进行病例报告。
结论
该病例提供了IgE依赖机制的证据，并提请注意胭脂红的触发剂量（1毫克），尽管每日可接受摄入量高达每公斤体重5.0毫克。
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