Dixon C M
New York University School of Medicine, New York, USA.
World J Urol. 1995;13(2):126-9. doi: 10.1007/BF00183629.
The use of right-angle laser fibers for the treatment of benign prostatic hyperplasia (BPH) has gained widespread acceptance over the past several years. The number of right-angle fibers introduced into the marketplace has continued to grow, but most fibers have not been evaluated thoroughly with properly designed clinical trials. The Urolase fiber has undergone the most extensive clinical trials conducted to date. This report reviews the significant clinical trials with particular emphasis on the comparison of transurethral prostatectomy with visual laser ablation of the prostate. From these initial results, it would appear that laser ablation using the Urolase fiber is a safe and effective surgical therapy for men with symptomatic BPH. From our analysis, it would appear that transurethral prostatectomy provides a greater degree of symptomatic improvement as compared with transurethral resection of the prostate. It is important to consider that these are some of the earliest clinical trials assessing the efficacy of laser prostatectomy and that technological advancements are likely to improve the clinical outcome.
在过去几年中,直角激光纤维用于治疗良性前列腺增生(BPH)已获得广泛认可。投放市场的直角纤维数量持续增长,但大多数纤维尚未通过设计合理的临床试验进行全面评估。Urolase纤维已进行了迄今为止最广泛的临床试验。本报告回顾了重要的临床试验,特别强调经尿道前列腺切除术与直视激光前列腺消融术的比较。从这些初步结果来看,使用Urolase纤维进行激光消融对于有症状的BPH男性是一种安全有效的手术治疗方法。从我们的分析来看,与经尿道前列腺切除术相比,经尿道前列腺切除术似乎能提供更大程度的症状改善。需要考虑的是,这些是评估激光前列腺切除术疗效的一些最早的临床试验,技术进步可能会改善临床结果。