Norris J P, Norris D M, Lee R D, Rubenstein M A
Department of Urology, Lutheran General Hospital, Park Ridge, Illinois.
J Urol. 1993 Nov;150(5 Pt 2):1612-4. doi: 10.1016/s0022-5347(17)35857-3.
Visual laser ablation of the prostate was performed on 108 patients (ages 44 to 84 years) as an outpatient procedure from May 1992 to October 1992. Preoperatively, the patients underwent digital rectal examinations, determination of prostate specific antigen levels and transrectal ultrasound guided biopsies when necessary to rule out the presence of prostate cancer. The Urolase laser fiber delivery system was used to transmit laser energy from a neodymium: YAG generator. For the 97 patients with preoperative and postoperative American Urological Association symptom index testing, scores decreased by an average of 12.59 (p < 0.001). For the 75 patients with preoperative and postoperative uroflow rates an average increase of 4.92 ml. per second (p < 0.001) was noted following the procedure. Only 3 patients required hospitalization for an average of 1.33 days. No patient required a blood transfusion. There have been no fluid or electrolyte abnormalities following visual laser ablation of the prostate. There have been no recognizable urethral strictures, deaths or postoperative sepsis. Only 3 patients experienced retrograde ejaculation. We found visual laser ablation of the prostate to be a cost-effective and less morbid alternative to traditional transurethral resection of the prostate.
1992年5月至1992年10月期间,对108例患者(年龄44至84岁)进行了门诊可视激光前列腺切除术。术前,患者接受直肠指检、测定前列腺特异性抗原水平,并在必要时进行经直肠超声引导下活检,以排除前列腺癌的存在。使用Urolase激光光纤传输系统从钕钇铝石榴石发生器传输激光能量。对97例术前和术后进行美国泌尿外科学会症状指数测试的患者而言,评分平均下降了12.59(p < 0.001)。对75例术前和术后进行尿流率检测的患者而言,术后平均每秒尿流率增加了4.92毫升(p < 0.001)。仅3例患者需要住院,平均住院1.33天。无患者需要输血。前列腺可视激光消融术后未出现液体或电解质异常。未出现可识别的尿道狭窄、死亡或术后败血症。仅3例患者出现逆行射精。我们发现,与传统经尿道前列腺切除术相比,前列腺可视激光消融术具有成本效益且发病率更低。