de la Rosette J J, te Slaa E, de Wildt M J, Debruyne F M
Department of Urology, University Hospital Nijmegen, The Netherlands.
World J Urol. 1995;13(2):98-103. doi: 10.1007/BF00183622.
Laser treatment of benign prostatic hyperplasia has enjoyed growing popularity among urologists over the last few years. Various applicators and techniques have been reported. Because this may result in a different overall performance, we performed a prospective randomized study comparing the results of treatment using the Ultraline fiber (n = 44) with that using the Urolase fiber (n = 49). Although different types of fibers and techniques were used, the results of this study were surprisingly similar for both fibers used. The uroflow for the Ultraline group increased from an average of 7.9 ml/s at baseline to 19.3 ml/s at 3 months and 16.9 ml/s at 6 months. In the patients treated with the Urolase fiber the uroflow improved from an average of 7.8 ml/s at baseline to 19.5 and 16.3 ml/s at 3 months and 6 months, respectively. The improvement in symptoms, reflected by changes in the I-PSS symptom scores, for the Ultraline group went from 21.0 at baseline to 7.9 at 3 months and 6.0 at 6 months. The Urolase patients improved from 21.0 at baseline to 8.2 and 5.6 at 3 and 6 month, respectively. The morbidity mainly consisted of a prolonged need for posttreatment catheterization and irritative symptoms lasting for about 2-4 weeks. From this study we conclude that the results achieved by laser treatment of the prostate using the Ultraline and Urolase fibers are both equivocal and excellent; however, the morbidity of these treatments remains considerable.
在过去几年中,激光治疗良性前列腺增生在泌尿外科医生中越来越受欢迎。已经报道了各种施源器和技术。由于这可能导致不同的整体性能,我们进行了一项前瞻性随机研究,比较了使用Ultraline光纤(n = 44)和使用Urolase光纤(n = 49)的治疗结果。尽管使用了不同类型的光纤和技术,但本研究中使用的两种光纤的结果惊人地相似。Ultraline组的尿流率从基线时的平均7.9 ml/s增加到3个月时的19.3 ml/s和6个月时的16.9 ml/s。在用Urolase光纤治疗的患者中,尿流率分别从基线时的平均7.8 ml/s改善到3个月和6个月时的19.5 ml/s和16.3 ml/s。I-PSS症状评分变化所反映的症状改善方面,Ultraline组从基线时的21.0降至3个月时的7.9和6个月时的6.0。Urolase组患者分别从基线时的21.0改善到3个月和6个月时的8.2和5.6。发病率主要包括治疗后需要长时间留置导尿管以及持续约2 - 4周的刺激性症状。从这项研究中我们得出结论,使用Ultraline和Urolase光纤进行前列腺激光治疗所取得的结果既不明确又很出色;然而,这些治疗的发病率仍然相当高。