Chakraborty A, Chowdhury B K, Bhattacharyya P
Department of Chemistry, School of Tropical Medicine, Calcutta, India.
Phytochemistry. 1995 Sep;40(1):295-8. doi: 10.1016/0031-9422(95)00047-b.
Two new carbazole alkaloids, designated as clausenol and clausenine, were isolated from an alcoholic extract of the stem bark of Clausena anisata. Their structures were established as 1-hydroxy-6-methoxy-3-methylcarbazole and 1,6-dimethoxy-3-methyl carbazole, respectively, from physical and chemical evidence and synthesis. Clausenol was found to be active against Gram-positive and Gram-negative bacteria and fungi.
从茴芹叶吴茱萸茎皮的乙醇提取物中分离出两种新的咔唑生物碱，分别命名为吴茱萸醇和吴茱萸碱。根据物理和化学证据及合成方法，确定它们的结构分别为1-羟基-6-甲氧基-3-甲基咔唑和1,6-二甲氧基-3-甲基咔唑。发现吴茱萸醇对革兰氏阳性菌、革兰氏阴性菌和真菌具有活性。
