Doherty M J, Spence D P, Davies P D
Aintree Chest Centre, Fazakerley Hospital, Liverpool, UK.
Tuber Lung Dis. 1995 Jun;76(3):196-200. doi: 10.1016/s0962-8479(05)80004-8.
A retrospective study of tuberculosis notifications in England and Wales published by the Office of Population Censuses and Surveys.
To analyse the rise in tuberculosis notifications in England and Wales by different sub groups over the time period 1982-91.
The average annual percentage change in tuberculosis notification rates (per 100,000) for the groups were analysed by age, sex, standard region and disease site.
The average annual increase in tuberculosis notifications from 1987-91 in females was +2.55 (95% confidence interval [CI] 0.5-4.7); males showed no significant change (-0.6%, 95% CI: -2.9 to +2.7). The increase was greater in younger subjects: 3.2% in females aged 25-44 (95% CI 0.9-5.5) and 4.3% in males aged 15-24 (95% CI 1.7-6.9). Only three standard regions showed an increase: the South East, the West Midlands, Yorkshire and Humberside. This increase was significant only in females from the South East, and was predominantly in non-respiratory tuberculosis.
The rise in tuberculosis notification rates from 1987-91 has been predominantly in females, in those under 65, has occurred in 3 regions, and predominantly in non-respiratory tuberculosis. The analysis highlights some of the inadequacies of the present notification system for tuberculosis.
对人口普查与调查办公室公布的英格兰和威尔士结核病通报情况进行的一项回顾性研究。
分析1982 - 1991年期间英格兰和威尔士不同亚组结核病通报数量的上升情况。
按年龄、性别、标准地区和疾病部位分析各亚组结核病通报率（每10万人）的年均百分比变化。
1987 - 1991年女性结核病通报数量的年均增长率为+2.55（95%置信区间[CI] 0.5 - 4.7）；男性无显著变化（-0.6%，95% CI：-2.9至+2.7）。年轻人群的增长幅度更大：25 - 44岁女性为3.2%（95% CI 0.9 - 5.5），15 - 24岁男性为4.3%（95% CI 1.7 - 6.9）。只有三个标准地区出现增长：东南部、西米德兰兹郡、约克郡和亨伯赛德郡。这种增长仅在东南部女性中显著，且主要为非呼吸道结核病。
1987 - 1991年结核病通报率的上升主要发生在65岁以下女性中，出现在3个地区，且主要为非呼吸道结核病。该分析凸显了当前结核病通报系统的一些不足之处。
