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[眼前节最严重化学性眼烧伤后带巩膜缘的角膜移植术]

[Keratoplasty with scleral rim after the most severe chemical eye burns of the anterior eye segment].

作者信息

Redbrake C, Buchal V

机构信息

Augenklinik, RWTH Aachen.

出版信息

Klin Monbl Augenheilkd. 1996 Mar;208(3):145-51. doi: 10.1055/s-2008-1035188.

DOI:10.1055/s-2008-1035188
PMID:8699771
Abstract

BACKGROUND

Corneo-scleral ulcerations and perforations are severe complications after most severe eye burns. One possibility to handle this situation is a keratoplasty with a scleral rim. This retrospective study was carried out to show the outcome after total replacement of the cornea after most severe eye burns.

PATIENTS

Between 1986 and 1991 we carried out 12 keratoplasties with a scleral rim in 9 most severely burnt eyes of 7 patients. In 9 cases this intervention was the first transplantation. In 3 eyes a re-keratoplasty had to be carried out.

RESULTS

All eyes could be saved after this surgical intervention, although all but two transplants failed. In eight cases the transplant decompensated and/or was replaced by scar tissue. Two transplants remained clear. Visual acuity was light perception in five cases, intact light projection in two cases, 1/35 in one case because of cataract formation and 0.8 in another case at the end of the observation period. The reasons for graft failure were multifactorial. Epithelial problems were the reason for graft failure in eight cases. Two of these also showed shrinkage of the eye lids with incomplete lid closure. In six cases severe vascularisation with scar formation was observed. It is remarkable that immunoreactions occurred only in four cases. This may be due to the fact that all patients were treated systemically with cyclosporin A. In one case the transplant failed after extensive surgery of the anterior segment.

CONCLUSION

Our results show that the keratoplasty with a scleral rim can save the eye in the difficult situation of corneo-scleral ulceration or perforation. Nevertheless a visual rehabilitation could not be achieved in seven of nine cases. But all eyes were in a satisfying condition for further smaller transplants to achieve better visual acuity.

摘要

背景

角膜巩膜溃疡和穿孔是大多数严重眼烧伤后的严重并发症。处理这种情况的一种可能性是进行带巩膜缘的角膜移植术。本回顾性研究旨在展示最严重眼烧伤后全角膜置换的结果。

患者

1986年至1991年间,我们对7例患者的9只最严重烧伤的眼睛进行了12次带巩膜缘的角膜移植术。9例该干预为首次移植。3只眼不得不进行再次角膜移植。

结果

尽管除2例移植外其他均失败,但所有眼睛经该手术干预后均得以挽救。8例移植失代偿和/或被瘢痕组织替代。2例移植保持透明。观察期末,5例视力为光感,2例光定位完整,1例因白内障形成视力为1/35,另1例为0.8。移植失败的原因是多因素的。上皮问题是8例移植失败的原因。其中2例还表现出眼睑收缩伴眼睑闭合不全。6例观察到严重血管化伴瘢痕形成。值得注意的是,仅4例发生免疫反应。这可能是由于所有患者均全身应用环孢素A。1例移植在前段广泛手术后失败。

结论

我们的结果表明,带巩膜缘的角膜移植术可在角膜巩膜溃疡或穿孔的困难情况下挽救眼球。然而,9例中有7例未能实现视力康复。但所有眼睛的状况均适合进一步进行较小的移植以获得更好的视力。

相似文献

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[Keratoplasty with scleral rim after the most severe chemical eye burns of the anterior eye segment].[眼前节最严重化学性眼烧伤后带巩膜缘的角膜移植术]
Klin Monbl Augenheilkd. 1996 Mar;208(3):145-51. doi: 10.1055/s-2008-1035188.
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Ophthalmologe. 1993 Dec;90(6):683-7.
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[Reconstructive surgery of extremely severe chemical eye burn with perforation].
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[Amniotic membrane transplantation with limbal stem cell transplantation as a combined procedure for corneal surface reconstruction after severe thermal or chemical burns].[羊膜移植联合角膜缘干细胞移植治疗严重热烧伤或化学烧伤后角膜表面重建]
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Corneoscleral transplantation for end stage corneal disease.角膜移植治疗终末期角膜疾病。
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