Kobayashi H, Itoh T, Itoh H, Konishi J
Department of Radiology and Nuclear Medicine, Kyoto University, Faculty of Medicine, Japan.
Abdom Imaging. 1995 Jul-Aug;20(4):341-7. doi: 10.1007/BF00203368.
Although duct ectasia due to mucus-producing pancreatic cancer has been well known, its occurrence in other organs has not been reported. We have studied the pathologic basis of the radiologic features in cases of mucus-producing cancer with intraductal extension.
We conducted a comparative study of detailed various radiographic images and pathological findings in 10 cases of mucus-producing cancers (four of mucus-producing pancreatic cancer, two of mucinous gastric cancer with diffuse lymphangitic liver metastasis, and four cases of bronchoalveolar cell carcinoma with cyst or cavity).
When mucus-producing cancer occurs in a secretory duct or extends into lymphatic ducts, the normal duct is dilated due to the mucus and increased internal pressure, leading to the formation of a cyst and cavity. Because of having the liquid property of mucus floating cancer cells, the lesion can easily progress to continuous ducts as well as regionally.
In cases of mucus-producing cancer with extension into the ductal structure not only in the pancreas but also in the lung and liver, continuous duct ectasis and cysts filled with mucus or cavities of all sizes made by the nature of the mucus may be detected by CT and US.
尽管由分泌黏液的胰腺癌导致的导管扩张已广为人知，但其在其他器官中的发生情况尚未见报道。我们研究了导管内扩展的分泌黏液性癌病例的放射学特征的病理基础。
我们对10例分泌黏液性癌（4例分泌黏液的胰腺癌、2例伴有弥漫性淋巴管性肝转移的黏液性胃癌、4例伴有囊肿或空洞的细支气管肺泡癌）的详细各种影像学图像和病理结果进行了对比研究。
当分泌黏液性癌发生于分泌导管或延伸至淋巴管时，由于黏液和内部压力增加，正常导管会扩张，导致囊肿和空洞形成。由于黏液具有使癌细胞漂浮的液体特性，病变不仅可在局部，还可沿连续的导管轻易进展。
在分泌黏液性癌累及胰腺、肺和肝的导管结构的病例中，CT和超声可能检测到由黏液性质形成的连续导管扩张以及充满黏液的囊肿或各种大小的空洞。
