Meinen K, Breinl H, Schmidt E W, Wellstein A
Gynecol Obstet Invest. 1978;9(6):319-24. doi: 10.1159/000301001.
100 patients with premature contractions were treated with the beta-adrenergic agent fenoterol for up to 9 weeks. To rule out a detrimental effect on the myocardium, the creatine kinase isoenzyme MB, which is specific to the myocardium, was determined regularly in addition to electrocardiographic monitoring. No pathological enzyme activity was detected even in long-term tocolytic therapy with the maximum dose.
100名早搏患者接受了β-肾上腺素能药物非诺特罗治疗,疗程长达9周。为排除对心肌的有害影响,除了进行心电图监测外,还定期测定心肌特异性的肌酸激酶同工酶MB。即使在最大剂量的长期宫缩抑制治疗中,也未检测到病理性酶活性。