Blazeby J M, Williams M H, Alderson D, Farndon J R
University Department of Surgery, Bristol Royal Infirmary, UK.
Br J Surg. 1995 Sep;82(9):1200-3. doi: 10.1002/bjs.1800820916.
Quality of life (QOL) assessment may improve the evaluation of treatment for oesophageal cancer but patient compliance using self completion questionnaires is often poor. The use of a proxy to estimate QOL might improve data collection from patients who are either unable or unwilling to complete the questionnaire. This study examined whether a doctor or patients' carers could accurately assess QOL using the QLQ-C30 questionnaire developed by the European Organisation for Research and Treatment of Cancer Study Group on Quality of Life. One doctor, 52 patients and 39 carers completed the instrument independently. Proxy and patient ratings were analysed for agreement using weighted kappa scores. Agreement was poor or moderate in most QOL scales and items (kappa < or = 60). This study demonstrates that a carer or doctor is not sufficiently accurate to postulate the patient's responses to the questionnaire. Quality of life data, therefore, should come from the patients themselves.
生活质量（QOL）评估可能会改善食管癌治疗的评估，但使用自填式问卷时患者的依从性往往较差。使用代理人来估计生活质量可能会改善从那些无法或不愿意完成问卷的患者那里收集数据的情况。本研究调查了医生或患者护理人员是否能够使用欧洲癌症研究与治疗组织生活质量研究小组开发的QLQ-C30问卷准确评估生活质量。一名医生、52名患者和39名护理人员独立完成了该问卷。使用加权kappa分数分析代理人和患者评分的一致性。在大多数生活质量量表和项目中，一致性较差或中等（kappa≤60）。本研究表明，护理人员或医生的准确性不足以推测患者对问卷的回答。因此，生活质量数据应该来自患者本人。
