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[门静脉供血与肝细胞癌的栓塞治疗]

[Portal vein supply and embolization therapy for hepatocellular carcinoma].

作者信息

Liu K, Lu J, Tan W

机构信息

Liver Cancer Institute, Shanghai Medical University.

出版信息

Zhonghua Yi Xue Za Zhi. 1995 Jul;75(7):403-5, 445.

PMID:7553158
Abstract

To prove the necessity and feasibility of portal vein embolization for the treatment of hepatocellular carcinoma (HCC), We observed the tumor vascularity and portal vein supply by vascular casting, Doppler pulse sonography and iodized oil embolization in 178 HCC noduls. Portal vascularity was found in 75.6% of noduls (34/45). In few noduls, which were smaller than 3cm in diameter, portal branches existed only without hepatic artery branches (7/35). Tumor portal blood supply was measured in 54.1% of noduls (59/109) by using Dopplar sonography. Portal tumor branch embolization was performed in 24 of patients with unreseatable HCC, all tumor noduls being filled with iodized oil. The combined portal vein and hepatic artery embolization was more effective than hepatic artery embolization in the control of the disease (P < 0.01).

摘要

为证明门静脉栓塞术治疗肝细胞癌(HCC)的必要性和可行性,我们通过血管铸型、多普勒脉冲超声及碘化油栓塞术对178个HCC结节的肿瘤血管及门静脉供血情况进行了观察。在45个结节中有75.6%(34/45)发现有门静脉血管。在少数直径小于3cm的结节中,仅存在门静脉分支而无肝动脉分支(7/35)。通过多普勒超声在109个结节中的54.1%(59/109)测量了肿瘤门静脉供血。对24例无法切除的HCC患者进行了门静脉肿瘤分支栓塞,所有肿瘤结节均被碘化油充填。门静脉和肝动脉联合栓塞在控制病情方面比肝动脉栓塞更有效(P<0.01)。

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