Farulla A, Naro G, Alimena G, Delfini A M, Ogis M, Pugliese D, Zingarelli S
Ann Ist Super Sanita. 1978;14(3):655-8.
The endocellular incorporation of asbestos fibres seems to be capable to induce on Chinese hamster cell cultures numerical and structural chromosome aberrations. In the present study asbestos fibres have been added at different concentrations to human cultured lymphocytes which have been harvested at 48 and 72 h, respectively. The results do not show significant difference in the distribution of chromatid and chromosome-type aberrations between the control cultures and the cultures treated with asbestos.
石棉纤维的细胞内掺入似乎能够在中国仓鼠细胞培养物中诱导数量和结构染色体畸变。在本研究中,已将不同浓度的石棉纤维添加到分别在48小时和72小时收获的人培养淋巴细胞中。结果显示,对照培养物与用石棉处理的培养物之间,染色单体和染色体型畸变的分布没有显著差异。