Karmeli Y, Stalnikowitz R, Eliakim R, Rahav G
Department of Internal Medicine, Hadassah Medical Center, Jerusalem, Israel.
Dig Dis Sci. 1995 Sep;40(9):2070-3. doi: 10.1007/BF02208680.
Quantitative cultures were carried out on samples from gastric juice obtained from 12 ambulatory patients with esophagitis before and one month after omeprazole therapy. An increase in the number of patients in whom gastric juice was culture-positive, as well as an increment in the bacterial counts were noted. The spectrum of microorganisms isolated from gastric juice was identical to the normal flora of the oral cavity, mainly alpha-hemolytic streptococci, corynebacteria, and Candida species. Thus, the counts of organisms within gastric contents are simply a reflection of swallowed oral microflora that were able to survive due to the less acidic environment.
对12例非卧床食管炎患者在奥美拉唑治疗前及治疗1个月后采集的胃液样本进行了定量培养。结果发现，胃液培养呈阳性的患者数量增加，细菌计数也有所上升。从胃液中分离出的微生物谱与口腔正常菌群相同，主要为α溶血性链球菌、棒状杆菌和念珠菌属。因此，胃内容物中的微生物数量仅仅反映了因酸性环境减弱而得以存活的吞咽口腔微生物群。
