González-Ramón N, Alava M A, Sarsa J A, Piñeiro M, Escartin A, Garcia-Gil A, Lampreave F, Piñeiro A
Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Spain.
FEBS Lett. 1995 Sep 11;371(3):227-30. doi: 10.1016/0014-5793(95)00882-a.
A major acute phase protein (pig-MAP) has been isolated from the sera of pigs after turpentine injection. The protein is the pig counterpart of a recently cloned human serum protein denominated PK-120, which is a putative substrate for kallikrein [Nishimura et al., 1995 FEBS Lett. 357, 207-211]. The protein exists in other mammalian species and it is also an acute phase protein, at least in the rat. Pig-MAP shows homology, as PK-120, with the heavy chain 2 (HC-2) of the inter-alpha-trypsin inhibitor superfamily but does not possess trypsin inhibitory activity.
一种主要的急性期蛋白（猪-MAP）已从注射松节油后的猪血清中分离出来。该蛋白是最近克隆的人血清蛋白PK-120的猪对应物，PK-120是激肽释放酶的一种假定底物[西村等人，1995年，《欧洲生物化学学会联合会快报》357，207 - 211]。该蛋白存在于其他哺乳动物物种中，并且至少在大鼠中也是一种急性期蛋白。猪-MAP与α-胰蛋白酶抑制剂超家族的重链2（HC-2）具有同源性，如同PK-120一样，但不具有胰蛋白酶抑制活性。
