与艾滋病相关的支原体在细胞膜中含有磷脂酶C。
AIDS-associated mycoplasmas possess phospholipases C in the membrane.
作者信息
Shibata K, Sasaki T, Watanabe T
机构信息
Department of Oral Bacteriology, Hokkaido University School of Dentistry, Sapporo, Japan.
出版信息
Infect Immun. 1995 Oct;63(10):4174-7. doi: 10.1128/iai.63.10.4174-4177.1995.
Abstract
Phosphatidylinositol- and phosphatidylcholine-hydrolyzing activities existed in the cell lysates of AIDS-associated Mycoplasma species, including Mycoplasma fermentans IID 812, M. fermentans incognitus, and M. penetrans GTU-54-6A1. These activities were found to be attributable to phospholipases C, because the water-soluble product from phosphatidylcholine digested by the cell lysate of M. fermentans IID 812 was phosphorylcholine. M. fermentans IID 812 was examined for localization of these enzymes, and it was found that they were associated with the membrane.
摘要
磷脂酰肌醇和磷脂酰胆碱水解活性存在于与艾滋病相关的支原体物种的细胞裂解物中，包括发酵支原体IID 812、发酵支原体隐匿株和穿透支原体GTU-54-6A1。这些活性被发现归因于磷脂酶C，因为发酵支原体IID 812细胞裂解物消化磷脂酰胆碱产生的水溶性产物是磷酸胆碱。对发酵支原体IID 812的这些酶进行了定位研究，发现它们与细胞膜相关。
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