Bagnasco M, Passalacqua G, Pronzato C, Albano M, Torre G, Scordamaglia A
Dept. of Internal Medicine, University of Genova, Italy.
J Endocrinol Invest. 1995 Apr;18(4):305-7. doi: 10.1007/BF03347818.
The Riedel's thyroiditis is an uncommon form of chronic thyroiditis characterized by an invasive fibrosclerosis of the gland, often involving the surrounding tissues. Usually, the only possible treatment is the surgical decompression of the tissues. We describe a case of aggressive Riedel's thyroiditis with severe compression and dislocation of trachea and esophagus. The surgical approach was uneffective, while an "ex juvantibus" steroid treatment, resulted in a dramatic regression of fibrosclerosis and a complete clinical remission. This report points out the possible effectiveness of corticosteroids in the treatment of selective disorders involving increased fibrogenesis.
里德尔甲状腺炎是一种罕见的慢性甲状腺炎,其特征为甲状腺的侵袭性纤维硬化,常累及周围组织。通常,唯一可行的治疗方法是对组织进行手术减压。我们描述了一例侵袭性里德尔甲状腺炎病例,该病例导致气管和食管严重受压并移位。手术方法无效,而“根据经验”使用的类固醇治疗使纤维硬化显著消退,临床症状完全缓解。本报告指出了皮质类固醇在治疗涉及纤维生成增加的选择性疾病方面可能具有的有效性。