Jobse C, Buntjer J B, Haagsma N, Breukelman H J, Beintema J J, Lenstra J A
Institute of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.
J Mol Evol. 1995 Sep;41(3):277-83.
The history of the abundant repeat elements in the bovine genome has been studied by comparative hybridization and PCR. The Bov-A and Bov-B SINE elements both emerged just after the divergence of the Camelidae and the true ruminants. A 31-bp subrepeat motif in satellites of the Bovidae species cattle, sheep, and goat is also present in Cervidae (deer) and apparently predates the Bovidae. However, the other components of the bovine satellites were amplified after the divergence of the cattle and the Caprinae (sheep and goat). A 23-bp motif, which as subrepeat of two major satellites occupies 5% of the cattle genome, emerged only after the split of the water buffalo and other cattle species. During the evolution of the Bovidae the satellite repeat units were shaped by recombination events involving subrepeats, other satellite components, and SINE elements. Differences in restriction sites of homologous satellites indicate a continuing rapid horizontal spread of new sequence variants.
通过比较杂交和聚合酶链反应（PCR）对牛基因组中丰富的重复元件的历史进行了研究。牛科动物A和牛科动物B短散在重复元件（SINE）都是在骆驼科动物和真正的反刍动物分化之后才出现的。牛科动物牛、绵羊和山羊的卫星序列中的一个31碱基对的亚重复基序在鹿科动物（鹿）中也存在，并且显然早于牛科动物出现。然而，牛卫星序列的其他成分是在牛和羊亚科（绵羊和山羊）分化之后扩增的。一个23碱基对的基序，作为两个主要卫星序列的亚重复序列，占据了牛基因组的5%，它是在水牛和其他牛物种分化之后才出现的。在牛科动物的进化过程中，卫星重复单元是由涉及亚重复序列、其他卫星成分和短散在重复元件的重组事件塑造的。同源卫星序列限制位点的差异表明新序列变体持续快速的水平传播。
