Sener R N
Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey.
Pediatr Radiol. 1995;25(5):385-6. doi: 10.1007/BF02021716.
The corpus callosum normally grows in a ventral to dorsal direction with the genu appearing first followed by posterior growth to form the body and splenium. In holoprosencephaly there usually is a malformation of the lamina terminalis which results in lack of formation of the corpus callosum. This paper presents a patient with mild, lobar holoprosencephaly in whom a different type of callosal dysgenesis was detected: the callosal body and splenium were apparently formed but the anterior parts were absent. The existence of this type of callosal dysgenesis appears to be in contrast to current theories on callosal development.
胼胝体通常从腹侧到背侧生长，膝部首先出现，随后向后生长形成体部和压部。在全前脑畸形中，终板通常存在畸形，导致胼胝体无法形成。本文报告了一名患有轻度叶型全前脑畸形的患者，在该患者中检测到一种不同类型的胼胝体发育不全：胼胝体部和压部明显形成，但前部缺失。这种类型的胼胝体发育不全的存在似乎与当前关于胼胝体发育的理论相悖。
