McMaster R P, Huffman J E, Fried B
Department of Biological Sciences, East Stroudsburg University, PA 18301, USA.
Parasitol Res. 1995;81(6):518-21. doi: 10.1007/BF00931795.
Golden hamsters (Mesocricetus auratus) were given intramuscular injections of dexamethasone and infected with Echinostoma caproni or E. trivolvis. All animals were necropsied on day 14 postinfection. Dexamethasone treatment at high doses resulted in increased parasite recovery. Decreased total white blood cell counts and decreased relative splenic weights were observed in corticosteroid-treated hamsters. Dexamethasone-treated animals also demonstrated significantly lower mean parasite dry weights for E. caproni. Specific serum IgG against the parasites was not detected in corticosteroid-treated hamsters on day 14 postinfection.
给金黄仓鼠（Mesocricetus auratus）肌肉注射地塞米松，然后感染卡氏棘口吸虫或三嵴棘口吸虫。所有动物在感染后第14天进行尸检。高剂量地塞米松治疗导致寄生虫回收率增加。在接受皮质类固醇治疗的仓鼠中观察到总白细胞计数减少和脾脏相对重量降低。接受地塞米松治疗的动物中，卡氏棘口吸虫的平均寄生虫干重也显著降低。在感染后第14天，接受皮质类固醇治疗的仓鼠中未检测到针对这些寄生虫的特异性血清IgG。
