增生性息肉中的印戒细胞癌。
Signet ring cell carcinoma in hyperplastic polyp.
作者信息
Zea-Iriarte W L, Itsuno M, Makiyama K, Hara K, Haraguchi M, Ajioka Y
机构信息
Second Dept. of Internal Medicine, Nagasaki University School of Medicine, Japan.
出版信息
Scand J Gastroenterol. 1995 Jun;30(6):604-8. doi: 10.3109/00365529509089797.
BACKGROUND
A polypectomy was performed on a 68-year-old woman who had three gastric hyperplastic polyps. A focal signet ring cell carcinoma was discovered in one of the polyps, which was 2.2 cm in diameter and was located in the antrum.
METHODS
To study the carcinoma's phenotype expression, special mucin histochemical stainings were performed.
RESULTS
The carcinoma infiltrated only into the mucosa. Intestinal metaplasia was scant. In the neoplasm neutral and foveolar mucin was predominant over acid mucin. The surrounding hyperplastic foveolar epithelium showed positivity for neutral mucin, and the intestinal metaplasia foci for acid mucin.
CONCLUSIONS
This neoplasm has a mixed composition of mucins and shares histochemical characteristics with the surrounding hyperplastic foveolar epithelium.
背景
对一名患有三个胃增生性息肉的68岁女性进行了息肉切除术。在其中一个直径为2.2 cm、位于胃窦的息肉中发现了局灶性印戒细胞癌。
方法
为研究该癌的表型表达，进行了特殊的黏液组织化学染色。
结果
癌仅浸润至黏膜层。肠化生少见。肿瘤中中性黏液和小凹黏液比酸性黏液占优势。周围增生的小凹上皮中性黏液呈阳性，肠化生灶酸性黏液呈阳性。
结论
该肿瘤具有黏液的混合成分，并与周围增生的小凹上皮具有共同的组织化学特征。
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