Singh H, Linas S L
Division of Nephrology and Hypertension, University of Colorado Health Sciences Center, Denver, USA.
Am J Kidney Dis. 1995 Oct;26(4):586-9. doi: 10.1016/0272-6386(95)90593-6.
Compulsive water drinking (psychogenic polydipsia) is a well-recognized clinical entity that is often seen in individuals with psychiatric disorders, especially schizophrenia. Although urinary tract abnormalities including enlarged bladders and hydronephrosis have been reported, the presence of chronic renal failure is rarely reported in this disorder. We report four patients with psychogenic polydipsia who presented with chronic renal failure due to obstructive uropathy in the absence of demonstrable anatomic causes of obstruction. The likely mechanism of functional obstructive uropathy is bladder failure due to a combination of excessive water ingestion, enlarged bladder volumes, and use of anticholinergic medications.
强迫性饮水（精神性烦渴）是一种公认的临床病症，常见于患有精神疾病的个体，尤其是精神分裂症患者。尽管已有报道称存在包括膀胱增大和肾积水在内的泌尿系统异常，但在这种病症中很少有慢性肾衰竭的报道。我们报告了4例精神性烦渴患者，他们在没有明显解剖学梗阻原因的情况下，因梗阻性尿路病出现了慢性肾衰竭。功能性梗阻性尿路病的可能机制是由于过量饮水、膀胱容量增大和使用抗胆碱能药物共同作用导致的膀胱功能衰竭。
