Herbert R, Gerr F, Luo J, Harris-Abbott D, Landrigan P J
Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, New York, USA.
Arch Environ Health. 1995 Sep-Oct;50(5):349-54. doi: 10.1080/00039896.1995.9935966.
Peripheral neuropathy developed in a 52-y-old roofer who was exposed to multiple solvents in one-ply roofing systems. Forty roofers who were exposed to various roofing systems were assessed by symptoms, occupational history, standardized physical examination, and measurement of vibrotactile thresholds of the upper and lower extremities. After exclusion of roofers who were predisposed to peripheral neuropathy, we detected abnormal vibrotactile thresholds in 42% (p < .001) of roofers' dominant toes and in 36% (p < .001) of roofers' nondominant toes; fewer roofers had abnormal sensory physical examinations or reported neuritic symptoms. Roofing workers may be at increased risk of peripheral neuropathy, perhaps resulting from exposure to solvents--particularly n-hexane, associated with one-ply roofing systems.
一名52岁的屋顶工患上了周围神经病变，他曾接触过单层屋顶系统中的多种溶剂。对40名接触过各种屋顶系统的屋顶工进行了症状、职业史、标准化体格检查以及上下肢振动觉阈值测量。在排除了易患周围神经病变的屋顶工后，我们发现42%（p < .001）的屋顶工优势足趾振动觉阈值异常，36%（p < .001）的非优势足趾振动觉阈值异常；有异常感觉体格检查或报告有神经症状的屋顶工较少。屋顶工可能患周围神经病变的风险增加，这可能是由于接触溶剂——尤其是与单层屋顶系统相关的正己烷所致。
