Nelson E A, Gibson B
J Wound Care. 1995 Oct;4(9):391-3.
Pyoderma gangrenosum is a rare condition which is sometimes associated with ulcerative colitis and Crohn's disease. The pathological basis is not completely understood but it may be caused by vasculitis. The lesions are typically said to have purple overhanging edges and a necrotic base. The condition may also occur with rheumatoid arthritis, multiple myeloma and leukaemia. The treatment of choice is systemic steroids but it may also respond to azathioprine, minocycline or clofazimine.
坏疽性脓皮病是一种罕见病症，有时与溃疡性结肠炎和克罗恩病相关。其病理基础尚未完全明确，但可能由血管炎引起。典型的病变表现为边缘呈紫色且有悬垂，底部坏死。该病症也可能与类风湿性关节炎、多发性骨髓瘤和白血病并发。首选治疗方法是全身使用类固醇，但对硫唑嘌呤、米诺环素或氯法齐明也可能有反应。
