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Cefotaxime versus ceftriaxone for the treatment of nosocomial pneumonia. Results of a multicenter study.

作者信息

Shah P M, Stille W

机构信息

Centre of Internal Medicine/Infectious Diseases, University Hospital, Frankfurt, Germany.

出版信息

Diagn Microbiol Infect Dis. 1995 May-Jun;22(1-2):171-2. doi: 10.1016/0732-8893(95)00083-m.

DOI:10.1016/0732-8893(95)00083-m
PMID:7587035
Abstract

Third-generation cephalosporins are the drugs of choice for serious nosocomial pneumonia; however, the recommended dosages are controversial. Our study compared two of these cephalosporins and showed that 2 g cefotaxime every 12 h and 4 g ceftriaxone once daily or 2 g every 12 h proved to be effective therapies for these chest indications.

摘要

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引用本文的文献

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Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults.成人医院获得性肺炎和呼吸机相关性肺炎临床实践指南。
Can J Infect Dis Med Microbiol. 2008 Jan;19(1):19-53. doi: 10.1155/2008/593289.
3
Guidelines for the management of hospital-acquired pneumonia in the UK: report of the working party on hospital-acquired pneumonia of the British Society for Antimicrobial Chemotherapy.
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J Antimicrob Chemother. 2008 Jul;62(1):5-34. doi: 10.1093/jac/dkn162. Epub 2008 Apr 29.
4
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Drugs. 2002;62(7):1041-89. doi: 10.2165/00003495-200262070-00005.
5
Cefotaxime. A reappraisal of its antibacterial activity and pharmacokinetic properties, and a review of its therapeutic efficacy when administered twice daily for the treatment of mild to moderate infections.头孢噻肟。对其抗菌活性和药代动力学特性的重新评估，以及对其每日两次给药治疗轻至中度感染时的治疗效果的综述。
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