Lampis G, Deidda D, Maullu C, Madeddu M A, Pompei R, Delle Monachie F, Satta G
Sezione di Microbiologia, Università di Cagliari, Italy.
J Antibiot (Tokyo). 1995 Sep;48(9):967-72. doi: 10.7164/antibiotics.48.967.
A series of new compounds with antiviral properties were isolated from a Bacillus sp. strain B-60. They were named sattabacin (1), hydroxysattabacin (2), sattazolin (3) and methylsattazolin (4). The biologically active compounds were recovered from fermentation broth by ethyl acetate extraction and silica-gel column fractionation. Their antiviral activity was mainly expressed against the Herpes simplex viruses type 1 and 2. The compound 3 showed a selective inhibition of protein synthesis in Herpesvirus-infected cells.
