Telch M J, Schmidt N B, Jaimez T L, Jacquin K M, Harrington P J
Department of Psychology, University of Texas at Austin 78712, USA.
J Consult Clin Psychol. 1995 Oct;63(5):823-30. doi: 10.1037//0022-006x.63.5.823.
Panic disorder (PD) is associated with significant social and health consequences. The present study examined the impact of treatment on PD patients' quality of life. Patients (N = 156) meeting DSM-III-R (Diagnostic and Statistical Manual of Mental Disorders [3rd ed., rev.]; American Psychiatric Association, 1987) criteria for PD with agoraphobia were randomly assigned to group cognitive-behavioral treatment (CBT) or a delayed-treatment control. An assessment battery measuring the major clinical features of PD as well as quality of life was administered at baseline (Week 0), post-treatment (Week 9) and 6-month follow-up (Week 35). Consistent with previous studies, PD patients displayed significant impairment in quality of life at intake. Compared with delayed-treatment control participants, CBT-treated participants showed significant reductions in impairment that were maintained at follow-up. Consistent with prediction, anxiety and phobic avoidance were significantly associated with quality of life, whereas frequency of panic attacks was not.
惊恐障碍（PD）会带来严重的社会和健康后果。本研究考察了治疗对惊恐障碍患者生活质量的影响。符合《精神疾病诊断与统计手册》第三版修订版（DSM-III-R；美国精神病学协会，1987年）中伴有广场恐惧症的惊恐障碍标准的患者（N = 156）被随机分配到团体认知行为治疗（CBT）组或延迟治疗对照组。在基线期（第0周）、治疗后（第9周）和6个月随访期（第35周）进行了一系列评估，测量惊恐障碍的主要临床特征以及生活质量。与先前的研究一致，惊恐障碍患者在入组时生活质量存在显著损害。与延迟治疗对照组参与者相比，接受CBT治疗的参与者在损害方面有显著降低，且在随访期保持这一效果。与预测一致，焦虑和恐惧回避与生活质量显著相关，而惊恐发作的频率则不然。
