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麻疹病毒疫苗接种后的神经系统并发症。1971年至1977年间所见病例的评估(作者译)

[Neurological complications following measles virus vaccination. Evaluation of the cases seen between 1971--1977 (author's transl)].

作者信息

Allerdist H

出版信息

Monatsschr Kinderheilkd (1902). 1979 Jan;127(1):23-8.

PMID:759838
Abstract

Within 11 days following vaccination with live virus vaccine in Hamburg 18 cases of neurological complications have been observed between 1971--1977, including 2 cases of abortive encephalitis. A causal connection was assumed only when the onset of symptoms was later than on the 7th day after the vaccination. The following parameters were evaluated; clinical symptoms, laboratory data, seasonal distribution of the neurological complications and their relationship to the total number of vaccinations, and the different results of studies from various countries using the same vaccine strain (Schwarz). The age disposition to convulsions following measles vaccination is comparable to convulsive reactions after smallpox vaccination.

摘要

1971年至1977年间,在汉堡接种活病毒疫苗后的11天内,观察到18例神经并发症病例,其中包括2例轻型脑炎。仅当症状发作晚于接种疫苗后的第7天时,才假定存在因果关系。评估了以下参数:临床症状、实验室数据、神经并发症的季节分布及其与接种总数的关系,以及各国使用相同疫苗株(施瓦茨株)的不同研究结果。麻疹疫苗接种后惊厥的年龄倾向与天花疫苗接种后的惊厥反应相当。

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