Joob A W, Haines G K, Kies M S, Shields T W
Department of Surgery, Northwestern University Medical School, Chicago, IL 60611, USA.
Ann Thorac Surg. 1995 Jul;60(1):217-22.
Primary malignant melanoma of the esophagus is a rare disease. A case is reported and the newer diagnostic techniques of immunohistologic identification of the tumor by positive reaction to the HMB-45 antigen, as well as immunoscintigraphy with Technetium-99m-labeled melanoma monoclonal antigen for the demonstration of distant metastasis, is presented. A current review of the literature on this uncommon tumor is presented, and treatment options are discussed. A total esophagectomy remains the treatment of choice. Four long-term (> 5 years) survivors after adequate surgical removal have been recorded in the literature.
原发性食管恶性黑色素瘤是一种罕见疾病。本文报告了一例病例，并介绍了通过对HMB - 45抗原呈阳性反应进行肿瘤免疫组织学鉴定的新诊断技术，以及使用锝 - 99m标记的黑色素瘤单克隆抗原进行免疫闪烁显像以显示远处转移的技术。本文对关于这种罕见肿瘤的文献进行了综述，并讨论了治疗选择。全食管切除术仍然是首选治疗方法。文献中记录了4例经充分手术切除后存活超过5年的长期存活者。
