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结肠黑变病还是黏膜缺血?一例报告。

Melanosis coli or mucosa ischemia? A case report.

作者信息

Fleischer I, Bryant D

出版信息

Ostomy Wound Manage. 1995 May;41(4):44, 46-7.

PMID:7598783
Abstract

The presence of a black or brown stoma may indicate a serious problem, such as a necrotic stoma, or may be the result of a benign pigmentation disorder known as melanosis coli. Melanosis coli is caused by anthraquinone laxative abuse and has no associated morbidity. The case report involves a 63 year old white female admitted to the hospital emergency room. Secondary to uterine choriocarcinoma, an end sigmoid colostomy was created. The mucosa was moist but black, despite the fact that the serosa had been pink and bled easily. Biopsy revealed neither necrotic stoma nor infarcted bowel but melanosis coli related to the patient's 20 year history of laxative use for chronic constipation. Melanosis coli does not require medical or surgical intervention and is considered a benign pigmentation disorder. However, knowledge of this condition and of the bowel patterns and habits of patients prior to their ostomy surgery, is essential to establishing the differential diagnosis for a brown or black stoma.

摘要

黑色或棕色造口的出现可能表明存在严重问题,如坏死性造口,也可能是一种称为结肠黑变病的良性色素沉着障碍的结果。结肠黑变病是由蒽醌类泻药滥用引起的,且无相关发病率。该病例报告涉及一名63岁的白人女性,她因子宫绒毛膜癌入院急诊室。继发于子宫绒毛膜癌,行乙状结肠末端造口术。尽管浆膜呈粉红色且易出血,但黏膜湿润却呈黑色。活检显示既无坏死性造口也无肠梗死,而是与患者因慢性便秘使用泻药20年的病史相关的结肠黑变病。结肠黑变病不需要药物或手术干预,被认为是一种良性色素沉着障碍。然而,了解这种情况以及患者在造口手术前的肠道模式和习惯,对于对棕色或黑色造口进行鉴别诊断至关重要。

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