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肾移植后附着点病和非典型痛风性关节炎:一项病例对照研究。

Enthesopathy and atypical gouty arthritis following renal transplantation: a case control study.

作者信息

Cohen M R, Cohen E P

机构信息

Department of Medicine, Medical College of Wisconsin, Milwaukee, USA.

出版信息

Rev Rhum Engl Ed. 1995 Feb;62(2):86-90.

PMID:7600077
Abstract

AIMS

To define associations and causative factors in a musculotendinous pain syndrome occurring after kidney transplantation.

METHODS

A case-control study was performed. Cases were identified clinically; transplant controls were matched for age, sex, date and type of transplant, and dialysis controls were matched for age, sex, and race.

RESULTS

All cases had enthesitis and five of seven later developed gouty arthritis. None of the controls had findings. The plasma uric acid was significantly greater in cases compared to both control groups.

CONCLUSIONS

A painful musculotendinous syndrome may occur after kidney transplantation. The development of gouty arthritis in five of the seven kidney transplant patients suffering from this syndrome and significant hyperuricemia compared with controls suggested an unusual pattern of gout arthropathy.

摘要

目的

确定肾移植后发生的肌腱疼痛综合征的关联因素和致病因素。

方法

进行了一项病例对照研究。通过临床诊断确定病例;移植对照组在年龄、性别、移植日期和类型方面进行匹配,透析对照组在年龄、性别和种族方面进行匹配。

结果

所有病例均有附着点炎,7例中有5例后来发展为痛风性关节炎。对照组均无相关发现。与两个对照组相比,病例组的血浆尿酸显著更高。

结论

肾移植后可能发生疼痛性肌腱综合征。7例患有该综合征的肾移植患者中有5例发生痛风性关节炎,且与对照组相比有明显的高尿酸血症,提示痛风性关节病的一种不寻常模式。

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