Kawakami K
Department of Radiology, Jikei University School of Medicine.
Kaku Igaku. 1994 Nov;31(11):1385-90.
Radionuclide study for pulmonary diseases is divided in three large categories, respiratory function of ventilation and perfusion, non-respiratory function such as mucocilliary movement, epithelial permeability, and tumor imaging. Ventilation and perfusion scintigraphy are useful for the diagnosis and follow up of pulmonary embolism, obstructive lung disease, etc. A new ventilatory agent, 99mTc-technegas, is now available and many studies with this gas have been reported. As a tumor imaging agent, 201TlCl is coming popular for the diagnosis of lung cancer and early detection of metastatic lesions. Tumor detection with 99mTc-MIBI is also tried to differentiate the malignant tumor from the benign process. As applications of nuclear medicine for the interstitial lung disease, 67Ga scintigraphy and measurement of epithelial permeability with 99mTc-DTPA are available for an evaluation of activity of the disease and damage of lung epithelial integrity. In this report, significance and useful application of the radionuclide methods were summarized.
通气和灌注的呼吸功能、诸如黏液纤毛运动、上皮通透性等非呼吸功能以及肿瘤显像。通气和灌注闪烁扫描术对肺栓塞、阻塞性肺病等的诊断及随访很有用。一种新的通气剂99mTc-锝气体现已可用，并且已有许多关于这种气体的研究报告。作为一种肿瘤显像剂，201TlCl在肺癌诊断和转移灶的早期检测中越来越受欢迎。也尝试用99mTc-MIBI进行肿瘤检测以鉴别恶性肿瘤与良性病变。作为核医学在间质性肺病中的应用，67Ga闪烁扫描术以及用99mTc-DTPA测量上皮通透性可用于评估疾病活动度和肺上皮完整性的损害。在本报告中，总结了放射性核素方法的意义及有用的应用。
