Thanner J, Freij-Larsson C, Kärrholm J, Malchau H, Wesslén B
Department of Orthopedics, Sahlgren Hospital, Göteborg, Sweden.
Acta Orthop Scand. 1995 Jun;66(3):207-14. doi: 10.3109/17453679508995525.
We evaluated the mechanical, chemical and clinical properties of Boneloc cement using radiostereometry and a series of laboratory tests. Compared to a standard cement (Palacos) the new cement displayed reduced tensile strength, elastic modulus, curing and glass transition temperatures. The amount of MMA extracted during 3 weeks in methanol was smaller for the Boneloc, but the total amount of released monomers was larger. The adhesion to stainless steel and bone did not differ. Radiostereometric analysis during the first postoperative year in 30 patients randomized to fixation of hip prostheses using either of the 2 cements displayed increased proximal migration of the cup and increased stem subsidence when Boneloc had been used. Part of the stem subsidence occurred inside the cement mantle. On the basis of these findings, we conclude that the inferior fixation in the Boneloc group is mainly caused by its mechanical properties. Other mechanisms, such as increased release of monomers, may also be important.
我们使用放射性立体测量法和一系列实验室测试评估了Boneloc骨水泥的力学、化学和临床特性。与标准骨水泥（Palacos）相比，新型骨水泥的拉伸强度、弹性模量、固化温度和玻璃化转变温度均有所降低。Boneloc骨水泥在甲醇中3周内提取的甲基丙烯酸甲酯量较少，但释放的单体总量较大。其与不锈钢和骨的黏附性并无差异。在30例随机使用这两种骨水泥之一进行髋关节假体固定的患者术后第一年的放射性立体测量分析显示，使用Boneloc骨水泥时髋臼杯近端移位增加，假体柄下沉增加。部分假体柄下沉发生在骨水泥壳内。基于这些发现，我们得出结论，Boneloc组固定效果较差主要是由其力学性能导致的。其他机制，如单体释放增加，可能也很重要。
