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对发育中的人类神经视网膜的光学显微镜研究。

A light microscopic study of the developing human neural retina.

作者信息

Rhodes R H

出版信息

Am J Anat. 1979 Feb;154(2):195-209. doi: 10.1002/aja.1001540206.

DOI:10.1002/aja.1001540206
PMID:760492
Abstract

Human embryonic and fetal eyes from 4 mm to 200 mm crown-rump length (26 days to 21 weeks of gestation) were studied in 0.75-micron sections impregnated with silver and toned with gold. The layer of Chievitz was formed by an inward migration of ganglion-cell and Müller-cell nuclei from the outer neuroepithelium and then, after further changes in nuclear location, the layer of Chievitz was cleared of ganglion-cell nuclei to become the definitive inner plexiform layer. Müller-cell nuclei later populated all retinal layers in the fetus. The argyrophilic Müller-cell cytoplasm associated with neuronal development is discussed in relation to glia-neuron interactions, with emphasis on the particular needs of retinal tissue.

摘要

对妊娠26天至21周、头臀长4毫米至200毫米的人类胚胎和胎儿眼睛进行了研究,制成0.75微米厚的切片,用银浸染并以金调色。奇维茨层是由神经节细胞核和米勒细胞核从外神经上皮向内迁移形成的,随后在核位置进一步变化后,奇维茨层中的神经节细胞核消失,成为最终的内网状层。米勒细胞核后来分布于胎儿的所有视网膜层。文中结合神经胶质-神经元相互作用讨论了与神经元发育相关的嗜银性米勒细胞胞质,重点是视网膜组织的特殊需求。

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